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Oklahoma State University

Recent Publications

Device (HIFU/proton) and nanoparticles (imageable & thermosensitive)

Hoopes PJ, Moodie KL, Petryk AA, PetryK. Sechrist S, Gladstone DJ, Steimetz NF, Veliz FA JD, Bursey AA, Wagner RJ, Ranjan A, Dugat D, Burney MC, Fiering SN. Hypo-fractionated radiation, magnetic nanoparticle hyperthermia and a viral immunotherapy treatment of spontaneous canine cancer; Proceedings Volume 10066, Energy-based treatment of tissue and assessment IX, 1006605 (2017); doi: 10.1117/12/2256213 

VanOsdol J, Ektate K, Ramasamy S, Maples D, Collins W, Malayer J, Ranjan A, Sequential HIFU heating and nanobubble encapsulation provide efficient drug penetration from stealth and temperature sensitive liposomes, J Control Release. 2016 Dec 30;247:55-63.

Ektate K, Kapoor A, Maples D, Tuysuzoglu A, VanOsdol J, Ramasami S, Ranjan A. Motion compensated Ultrasound imaging allows thermometry and image guided drug delivery, Theranostics. 2016 Aug 14;6(11):1963-74

Sethuraman SN, Ranjan A. Neoantigen activation, protein translocation and targeted drug delivery in combination with radiotherapy. Therapeutic Delivery, 2016 Jun;7(6):377-85

Ranjan A, Benjamin CJ, Negussie AH, Chokshi S, Chung PH, Volkin D, Yeram N, Linehan WM, Dreher MR, Pinto PA, Wood BJ. Biodistribution and efficacy of low temperature sensitive liposome encapsulated docetaxel combined with mild hyperthermia in a mouse model of prostate cancer, Pharm Res. 2016 Jun 24.

Wardlow R, BingC, VanOsdol J, Maples D, Wodzak M, Harbeson M, Nofiele J, Staruch R, Ramachandran A, Malayer J, Chopra R, Ranjan A,Targeted antibiotic delivery using temperature sensitive liposomes and magnetic resonance guided high intensity focused ultrasound hyperthermia, International Journal of Hyperthermia, 2016 May;32(3):254-64.

Chenchen Bing, Joris Nofiele, Robert Michael Staruch, Michelle Ladouceur-Wodzak, Yonatan Chatzinoff, Ashish Ranjan, Rajiv Chopra, Localized hyperthermia in rodent models using an MRI-compatible high-intensity focused ultrasound system, International Journal of Hyperthermia, 2015 Dec;31(8):813-22.

Maples D, Newhardt R, Kapoor A, Ranjan A. Ultrasound-imageable low temperature sensitive liposomes for image guided tumor drug delivery, International Journal of Hyperthermia, 2015 Sep;31(6):674-85.

Fernando R, Senavirathna LK, Maples D, Zheng Y, Polf, JC, Piao D, Bartels K, Benton E, Ranjan A,Hyperthermia sensitization and proton beam guided liposomal drug delivery for targeted tumor therapy, Pharm Res. Nov;31(11):3120-6

Fernando R, Downs J, Ranjan A, MRI-guided Hyperthermia for Drug Delivery: Combining The Properties Of Imaging and Therapy, Pharm Res. 2013 Nov;30(11):2709-17

Senavirathna LK., Fernando R, Maples D, Zheng Y, Polf JC., Ranjan A, Tumor Spheroids as an In vitro Model for Determining the Therapeutic Response to Proton Beam Radiotherapy and Thermally Sensitive Nanocarriers, Theranostics. 2013 Aug 21;3(9):687-91

De Souza PC, Ranjan A, Towner RA. Nanoformulations for therapy of pancreatic and liver cancers, Nanomedicine (Lond.) (2015) 10(9), 1515–1534

Amalou H, Negussie AH, Ranjan A, Chow L, Xu S, Kroeger C, Neeman Z, O’Grady P. N, Wood BJ,Electrically Conductive Catheter Inhibits Bacterial Colonization, Journal of Vascular and Interventional Radiology,  2014;25:797–802

Kasimanickam RK, Ranjan A,Asokan GV,Kasimanickam VR, Kastelic JP.Prevention and treatment of biofilms by hybrid technologies, Int J Nanomedicine. 2013;8:2809-19

Erythrocyte targeting/nano-bioscavening (Last 4 years)

Sahoo K, Karumuri S, Hikkaduwa Koralege RS, Flynn NH, Hartson S, Liu J, Ramsey JD, Kalkan K, Pope C, Ranjan A, Molecular and biocompatibility characterization of red blood cell membrane targeted and cell penetrating peptide-modified polymeric nanoparticles, Mol Pharm. 2017 May 15. doi: 10.1021/acs.molpharmaceut.7b00053. 

Sahoo K, Koralege RS, Flynn N, Koteeswaran S, Clark P, Hartson S, Liu J, Ramsey JD, Pope C, Ranjan A,.“Nanoparticle targeting to erythrocyte via the glycophorin A affinity ligand enhances binding without impacting cellular function”, Pharm Res. 2016 May;33(5):1191-203.

Nicholas Flynn; Ç. Özge Topal; Rangika S Hikkaduwa Koralege, Steve Hartson, Ashish Ranjan, Jing Liu, Carey Pope, Encapsulation of Bovine Serum Albumin with a Library of PEGylated Cationic Copolymers.  Materials Science and Engineering C,2016 May 1;62:524-31.

Carey N Pope, Chibuzor Uchea, Nicholas Flynn, Kirstin Poindexter, Liyi Geng, Stephen  Brimijoin, Steve Hartson, Ashish  Ranjan, Joshua D Ramsey, Activity- and Inhibitor-Based Characterization of Cationic Copolymer-Encapsulated Recombinant Human Butyrylcholinesterase, 2015 Dec 1;98(3):531-9

Hester K, Liu J, Flynn N, Sultatos LG, Geng L, Brimijoin S, Ramsey JD, Hartson S, Ranjan A, Pope C. Polyionic complexes of butyrylcholinesterase and poly-l-lysine-g-poly(ethylene glycol): Comparative kinetics of catalysis and inhibition and in vitro inactivation by proteases and heat. Chem Biol Interact. 2017 Sep 25;275:86-94.