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Dr. Ranjan's Team Receives OARS Grant

August 2019

Congratulations to Dr. Ashish Ranjan and his team on receiving a 2-year Oklahoma Applied Research Support program grant. Provided by the Oklahoma Center for the Advancement of Science and Technology, the grant totals $310,000.

Ranjan's team will be developing a minimally invasive pet sterilization technology. CVM collaborators on this project include Drs. Kimberly Carter, Lionel Dawson, Candace Lyman, and Jerry Malayer.

Dr. Ranjan's Team Receives Grant

July 2019

Congratulations to Dr. Ashish Ranjan and his team on receiving a 5-year RO1 grant totaling nearly $1.7 million from the National Cancer Institute (NCI) at the National Institutes of Health!

The RO1 grant was also selected for the prestigious NCI MERIT Award, which will ensure extended funding to Dr. Ranjan's lab. NCI is using the MERIT Award to give eligible investigators the opportunity to obtain up to seven years of support. The funding comes in two segments with the first being an initial 5-year award and the second being an extension of up to two additional years. Recipients of the extension are based on an expedited NCI review of the team's accomplishments during the initial funding segment.

CVM collaborators on this proposal include Drs. Shitao Li, Jerry Ritchey, Danielle Dugat, and Jerry Malayer.

Focused Ultrasound Veterinary Cancer Clinical Trial Showing Promising Results

April 2018

A team of veterinarians led by Dr. Ashish Ranjan is making headway in the use of focused ultrasound to treat cancer in companion animals. In one study, his team is exploring the use of focused ultrasound for soft tissue tumors in dogs and cats. One of their patients, Oreo, is cancer free thanks to this treatment. Read more at Oreo's story.

In a second study, Ranjan and Dr. Danielle Dugat are working with companion animals suffering from hard-to-heal wounds. They are investigating focused ultrasound's ability to speed wound healing.

Read more about both clinical trials at Advantages of Focused Ultrasound in Veterinary Medicine.

Ranjan Lab receives funding from Focused Ultrasound Foundation for Dog clinical trials

January 2018

Congratulations to Drs. Ashish Ranjan, Danielle Dugat, Jerry Malayer, and Jerry Ritchey on receiving funds for a new study! The team received a $100,000 grant from the Focused Ultrasound Foundation for "Investigation of focused ultrasound mediated enhancement of chronic non-healing wound antimicrobial therapy in client-owned dogs."

Nonhealing wounds caused by biofilm-forming bacteria are hard to treat and often require long duration antimicrobial treatment, extensive surgical debridement and in many cases, limb amputations. The team will be investigating the effect of a high frequency ultrasound unit on wound healing associated with elbow hygromas in dogs to try to find an alternate modality to treatment.

An elbow hygroma is a swelling that occurs over the point of the elbow from repeated trauma. The swelling often opens up and becomes infected. These wounds are traditionally challenging to treat surgically or medically.

Congratulations to Sri Nandhini Sethuraman on receiving 2nd place in the graduate student category at a December "End2Cancer: Emerging Nanotechnology and Drug Delivery Applications for Cancer" conference held in Oklahoma City!

Graduate Student Recognized

January 2018

This national conference brought together leaders in the field who discussed new and emerging concepts and technologies and challenges in clinical advancement of nanomedicine. Sethuraman is mentored by Dr. Ashish Ranjan in the Department of Physiological Sciences. Co-authors on this study included Harshini Ashar, Cristina Munteanu, Mohit Pratap Singh, Dr. Jerry Ritchey and  Dr. Jerry Malayer. 

Wardlow and Nanomedicine Lab Members Win Best Paper of the Year

March 2017

Congratulations to Rachel Wardlow, DVM ('13). and lab colleagues on earning the 2017 International Journal of Hyperthermia Best Paper Award by a junior investigator in the Biology category!

Wardlow is a post-DVM fellow in Dr. Ashish Ranjan's Targeted Therapy and Nanomedicine Laboratory. Her research focuses on chronic non-healing wound infections that require long duration antibiotic therapy.

Wardlow, R., Bing, C., VanOsdol, J., Maples, D., Ladouceur-Wodzak, M., Harbeson, M. Nofiele, J., Staruch, R., Ramachandran, A., Malayer, J., Chopra, R., Ranjan, A. (2016). Targeted antibiotic delivery using low temperature-sensitive liposomes and magnetic resonance-guided high-intensity focused ultrasound hyperthermia. Int J Hyperthermia, 32(3), 254-264. doi:10.3109/02656736.2015.1134818.