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Oklahoma State University

Team Members

Director

Ashish Ranjan, B.V.Sc., Ph.D.
Kerr Chair for Biomedical Laser and Biophotonics

ashish ranjan

Dr. Ranjan earned his BVSc degree (DVM equivalent) from Madras Veterinary College, in Chennai, India. He earned a PhD in Biomedical and Veterinary Sciences from Virginia Tech. Dr. Ranjan then was a Visiting Fellow at the Center for Interventional Oncology, Department of Radiology and Imaging Sciences at the National Institutes of Health.

Members

Harshini K Ashar, BVSc, MVSc

harshini ashar

Dr. Ashar received her BVSc from Nagpur Veterinary College in India and her MVSc from Bombay Veterinary College in India. She is currently a Ph.D. student in the Nanomedicine and Targeted Therapy Lab.

Research interests-: Cancer Immunotherapy, HIFU guided drug delivery

Current project: Investigate the effects of HIFU induced anti-tumor response and immunity and mechanism of abscopal effect in mouse melanoma model.

Nandhini Sethuraman, B.V.Sc., MS, PhD
Post-Doctoral Fellow

Research Interest: Hybrid drug delivery system, HIFU

Kalyani Ektate, PhD, Post-Doctoral Fellow

kalyani ektate

Areas of Interest: Cancer Stem Cell targeting, HIFU mediated drug delivery.

Michael Gorbet

mike gorbet

Michael-Joseph Gorbet obtained his Bachelor’s of Science degree in Chemistry in 2016, from Southwestern Oklahoma State University, Department of Chemistry and Physics. During his undergraduate education, he was involved in bioinorganic synthesis chemistry making contrast agents and oxidation catalysts for three years. Gorbet also participated in internships at both Georgia Tech University and the University of Hull, UK.

After a year as a Ph.D. student in the Chemistry and Biochemistry department at the University of Oklahoma, he transferred to Dr. Ranjan’s lab at Oklahoma State University as a National Science Foundation Bridge to the Doctorate Fellow and graduate research assistant. 

Gorbet  is a proficient synthetic chemist working with both organic and inorganic chemistry with a future aim in contributing to making a targeted cancer therapy using a nanoparticle-based delivery system.  Specific areas of current work and research interest include:

  • Nanoparticle synthesis for real-time imaging of immune response
  • Organic/Ligand Synthesis with Metal Complexation for cell-based targeting
  • Device induced nanoparticle synthesis for cancer therapy

Danny Maples
Postdoctoral fellow

Areas of Research: HIFU Guided Drug delivery, Nanoparticle synthesis

Cristina Munteanu, Ph.D.

cristina muteanu

Dr. Maria Cristina Munteanu obtained her Ph.D. degree in 2007 from the University of Bucharest, Department of Biochemistry and Molecular Biology, Romania. After a brief stint as a Lecturer at the University of Bucharest, Romania, she joined Oklahoma State University as a Research Associate in 2010. Munteanu is an experienced molecular biologist with a rich history of productivity in the proteoglycan, macrophage polarization, miRNA and lncRNA biology. Her current research is focused on understanding the impact of device directed particles on tumor stromal cells.  Specific areas of work include:

  • Macrophage polarization mechanisms
  • Role of extracellular matrix proteoglycans
  • Therapeutic target identification in cancer cell.

 

Mohit Singh

mohit singh

Mohit Singh earned his bachelor of veterinary science degree from Madras Veterinary College, India and his master’s in veterinary surgery from GBPUA&T, Pantnagar. He is currently a graduate student.

Singh research interests include:

  • Development of gene delivery nano-system to improve anti-tumor immunity
  • Development of nano drug delivery system for red blood cell targeting and in vivo imaging
  • Understand the impact of HIFU on anti-tumor immune response

Joshua VanOsdol

joshua vanosdolo

Joshua VanOsdol received a Bachelor’s of Science in Biology from Fairmont State University, WV. He is currently working on his Ph. D. at OSU. VanOsdol's current research focus is the development and evaluation of chemotherapeutic nanoparticles that exhibit theranostic properties.

Current research topics:

  • Echogenic temperature sensitive liposomes
  • Synergistic drug delivery modalities
  • Therapy induced changes in tumor microenvironment